Idiopathic thrombocytopenic purpura

Idiopathic thrombocytopenic purpura, is defined as an autoimmune haematological disorder characterised by an isolated low platelet count with a normal bone marrow in the absence of other causes of low platelets. It causes a characteristic red or purple bruise-like rash anywhere on the body (but primarily on the lower limbs) and an increased tendency to bleed. 

Initial treatment of patients with newly diagnosed ITP includes observation, a corticosteroid, and/or IVIG depending on platelet count and bleeding symptoms. Advise parents to avoid non-steroidal anti-inflammatories (NSAIDS).

Patients with life-threatening bleeding, regardless of platelet count, can be considered for combination therapy with corticosteroids, intravenous immunoglobulin (IVIG), and platelet transfusion.

Prognosis is good in children, with up to 80% achieving a spontaneous remission